STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_1402PFAM: isochorismatase hydrolase; KEGG: afw:Anae109_1088 isochorismatase hydrolase. (199 aa)    
Predicted Functional Partners:
Apre_1403
KEGG: gbm:Gbem_3769 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.782
Apre_0507
TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pca:Pcar_2216 NAD synthetase.
  
 
 0.550
Apre_1401
Hypothetical protein; KEGG: yen:YE0537 putative multi-drug efflux protein.
       0.541
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: bsu:BSU22830 NAD(P)H-dependent glycerol-3- phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 
 0.507
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.433
Apre_1404
KEGG: bcy:Bcer98_3299 alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; D- isomer specific 2-hydroxyacid dehydrogenase NAD-binding; Belongs to the AlaDH/PNT family.
     
 0.425
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.401
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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