Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
Score
Apre_1496UvrD/REP helicase; ATP-dependent DNA helicase. (851 aa)    
Predicted Functional Partners:
Apre_1497
PFAM: GCN5-related N-acetyltransferase; KEGG: acetyltransferase, GNAT family protein.
  
  
 0.801
Apre_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.694
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.691
Apre_1413
KEGG: bce:BC2815 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
  
 
 0.667
Apre_1495
PFAM: transcriptional regulator PadR family protein; KEGG: bcr:BCAH187_A0475 transcriptional regulator, PadR family.
       0.667
Apre_0897
KEGG: hypothetical protein.
  
     0.666
Apre_1516
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: rpi:Rpic_4263 transcriptional regulator, ArsR family.
 
  
 0.665
Apre_1494
PFAM: pseudouridine synthase; RNA-binding S4 domain protein; KEGG: bha:BH3273 16S pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
       0.662
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
  
 0.657
Apre_0163
KEGG: conserved hypothetical protein; K10401 kinesin family member 18/19.
  
     0.645
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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