STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIQ89607.1NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (253 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.933
SIQ89581.1
Nitrilase.
    
 0.884
SIQ36553.1
Signal transduction histidine kinase.
    
  0.864
SIQ14859.1
PAS domain S-box-containing protein.
    
  0.863
SIQ19074.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.856
SIR22847.1
NAD(P) transhydrogenase subunit alpha.
     
 0.856
SIR35951.1
NAD(P) transhydrogenase subunit alpha.
     
 0.856
SIQ62762.1
Dihydrolipoamide dehydrogenase.
     
 0.854
SIR22874.1
NAD(P) transhydrogenase subunit alpha.
     
 0.854
SIR35915.1
NAD(P) transhydrogenase subunit alpha.
     
 0.854
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
Server load: low (16%) [HD]