STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIQ96178.1Homoserine O-succinyltransferase; Belongs to the MetA family. (332 aa)    
Predicted Functional Partners:
SIQ96210.1
O-acetylhomoserine sulfhydrylase.
 
 
 0.980
SIR12670.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.920
SIQ70174.1
Homoserine dehydrogenase.
  
 
 0.918
SIR49425.1
O-acetylhomoserine sulfhydrylase.
 
 
 0.908
SIR50520.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.899
SIR48534.1
Cystathionine gamma-synthase.
 
 
 0.888
SIQ82250.1
Cystathionine gamma-synthase/methionine-gamma-lyase.
 
 
 0.873
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
 0.857
SIQ99228.1
Large subunit ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
   
    0.834
SIR03581.1
Cystathionine beta-lyase.
 
 
 0.813
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.