Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIR00549.13-methylfumaryl-CoA hydratase. (281 aa)    
Predicted Functional Partners:
SIQ30762.1
Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.931
SIQ30553.1
Catechol 2,3-dioxygenase.
 
  
 0.850
SIQ88396.1
Acyl transferase domain-containing protein.
     
  0.778
SIQ48639.1
Acetyltransferase.
    
  0.775
SIR00519.1
Glyoxylase, beta-lactamase superfamily II.
       0.773
SIQ79409.1
Short chain enoyl-CoA hydratase.
     
  0.772
SIR20175.1
3-hydroxyacyl-CoA dehydrogenase.
     
  0.772
SIQ31806.1
enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
     
  0.770
SIQ10255.1
acetyl-CoA synthetase.
     
  0.769
SIQ45868.1
fatty-acyl-CoA synthase.
     
  0.769
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.