STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR44443.1Formate dehydrogenase alpha subunit. (946 aa)    
Predicted Functional Partners:
SIR31471.1
Ni,Fe-hydrogenase III large subunit.
  
 0.999
SIR44409.1
Formate dehydrogenase delta subunit.
 
 0.999
SIR44471.1
Formate dehydrogenase beta subunit.
 0.998
SIR44490.1
Formate dehydrogenase gamma subunit.
 
 0.998
SIR42321.1
Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
0.995
nuoD
NADH dehydrogenase subunit C /NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 0.986
SIQ68846.1
Reductase C-terminal.
 
 
 0.986
SIQ85295.1
(2Fe-2S) ferredoxin.
  
 0.986
fdhD
FdhD protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 0.981
SIQ05536.1
NADH dehydrogenase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
 
 0.980
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
Server load: low (16%) [HD]