STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR51237.1Hypothetical protein. (241 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.853
SIR51216.1
Hypothetical protein.
       0.773
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
 
  0.634
SIQ40118.1
Helix-turn-helix.
  
  
  0.565
SIQ56399.1
Uncharacterized conserved protein, LabA/DUF88 family.
  
     0.537
SIQ55094.1
Methyltransferase domain-containing protein.
  
     0.535
SIR29904.1
Conjugal transfer/type IV secretion protein DotA/TraY.
  
     0.527
SIR47814.1
Sulfur-oxidizing protein SoxB; Belongs to the 5'-nucleotidase family.
     
 0.527
SIR31196.1
Hypothetical protein.
  
     0.515
SIR31149.1
Protein of unknown function DUF58.
  
     0.494
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.