STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrA-2Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (234 aa)    
Predicted Functional Partners:
SIQ47480.1
Peptide-methionine (R)-S-oxide reductase.
 
 0.993
SIQ20911.1
Cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE.
   
 0.986
SIQ26910.1
Thiol-disulfide isomerase or thioredoxin.
   
 0.986
SIR01581.1
Thiol:disulfide interchange protein DsbD.
   
 
 0.937
SIR37379.1
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
    
 
 0.918
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.897
SIQ36553.1
Signal transduction histidine kinase.
     
 0.545
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
  
 0.544
SIR12670.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.515
flgK
Flagellar hook-associated protein 1 FlgK.
    
   0.499
Your Current Organism:
Acidiphilium rubrum
NCBI taxonomy Id: 526
Other names: A. rubrum, ATCC 35905, Acidiphilum rubrum, strain OP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.