Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACZ08018.1Transcriptional regulator, XRE family; KEGG: hip:CGSHiEE_04620 putative prophage repressor CI. (229 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.970
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.805
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.682
ACZ09551.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.677
ACZ08015.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rlt:Rleg2_4171 ABC transporter related.
       0.620
ACZ08016.1
PFAM: inner-membrane translocator; KEGG: scl:sce7757 ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.
       0.620
ACZ08017.1
PFAM: inner-membrane translocator; KEGG: cvi:CV_2350 sugar ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.
       0.620
ACZ08014.1
Hypothetical protein.
       0.512
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.507
ACZ08012.1
Conserved hypothetical protein; Displays ATPase and GTPase activities.
       0.486
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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