STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ACZ08466.1PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: pca:Pcar_1631 thiamine biosynthesis protein ThiH. (472 aa)    
Predicted Functional Partners:
ACZ08428.1
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: pca:Pcar_1629 GTPases.
  
 0.943
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.899
ACZ10435.1
TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1605 NAD-reducing iron-only hydrogenase large subunit.
 
   
 0.818
ACZ07144.1
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sde:Sde_1113 hypothetical protein.
  
    0.781
ACZ07498.1
TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1605 NAD-reducing iron-only hydrogenase large subunit.
 
   
 0.771
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.723
ACZ08464.1
tRNA/rRNA methyltransferase (SpoU); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.723
ACZ08465.1
PFAM: Lytic transglycosylase catalytic; KEGG: sde:Sde_1778 LolC/E family lipoprotein releasing system, transmembrane protein.
       0.723
ACZ10302.1
Putative PAS/PAC sensor protein; PFAM: hydrogenase large subunit domain protein; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; SMART: PAS domain containing protein; KEGG: sfu:Sfum_1846 putative PAS/PAC sensor protein.
 
   
 0.717
ACZ10304.1
PFAM: hydrogenase large subunit domain protein; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: dps:DP2379 hydrogenase.
 
   
 0.704
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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