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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)    
Predicted Functional Partners:
ACZ09923.1
PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation.
  
 
 0.949
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.934
ACZ09023.1
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: sat:SYN_01255 O-acetyl-L-homoserine sulfhydrolase / O-acetyl-L-serine sulfhydrolase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase.
  
 
 0.923
ACZ07704.1
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: tdn:Suden_1565 DNA (cytosine-5-)- methyltransferase.
    
 0.918
ACZ09698.1
KEGG: tdn:Suden_1565 DNA (cytosine-5-)- methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.
    
 0.918
ACZ08684.1
KEGG: aha:AHA_2293 GAF domain-containing protein.
    
  0.903
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
 0.758
ACZ09024.1
KEGG: cju:C8J_1146 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.720
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
    0.720
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.715
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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