STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (281 aa)    
Predicted Functional Partners:
ACZ07261.1
KEGG: dal:Dalk_3807 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
   
 
 0.785
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.782
ACZ09059.1
PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: abu:Abu_0181 DNA/RNA helicase.
     
 0.759
ACZ09057.1
Hypothetical protein.
       0.732
ACZ07040.1
TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: apa:APP7_0902 D,D-heptose 1,7-bisphosphate phosphatase.
   
 
 0.680
ACZ09056.1
TIGRFAM: metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; NUDIX hydrolase; KEGG: scl:sce1090 hypothetical protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.677
ACZ08872.1
KEGG: uracil-DNA glycosylase; K03648 uracil-DNA glycosylase; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
   
 
 0.676
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 
 0.676
ACZ10949.1
PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: dds:Ddes_1159 HhH-GPD family protein.
   
 
 0.665
ACZ09055.1
PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: gur:Gura_0193 sun protein.
     
 0.633
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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