STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACZ09154.1KEGG: dol:Dole_3236 siroheme synthase. (145 aa)    
Predicted Functional Partners:
ACZ07891.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dat:HRM2_35960 HemD.
 
 
 0.995
ACZ07880.1
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dat:HRM2_02310 CbiL; Belongs to the precorrin methyltransferase family.
 
  
 0.942
ACZ07870.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1268 cobalamin (vitamin B12) biosynthesis CbiX protein.
  
 
 0.880
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.837
ACZ07360.1
Sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: wsu:WS1004 hypothetical protein.
 
  
 0.773
ACZ07895.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ppd:Ppro_0442 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
   
 0.771
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.715
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gur:Gura_4245 glutamate-1-semialdehyde aminotransferase.
 
   
 0.708
ACZ09155.1
KEGG: sun:SUN_1004 hypothetical protein.
       0.693
ACZ08532.1
TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vfm:VFMJ11_0394 endoribonuclease L-PSP, putative.
 
      0.687
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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