STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrDDihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (322 aa)    
Predicted Functional Partners:
ACZ09511.1
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: gsu:GSU1756 dihydroorotate dehydrogenase, electron transfer subunit, putative.
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.998
ACZ07665.1
TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_2748 putative trifunctional 2- polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein.
 
 0.997
ACZ09508.1
TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: afr:AFE_1463 dihydroorotase.
 
 0.996
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.986
pyrB
KEGG: cvi:CV_0369 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.983
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; protein of unknown function DUF201; KEGG: dat:HRM2_47760 CarB2; Belongs to the CarB family.
 
 
 0.982
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.969
ACZ07142.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2295 putative oxidoreductase.
 
 0.948
ACZ07429.1
TIGRFAM: sulfite reductase, subunit B; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: aha:AHA_2576 anaerobic sulfite reductase subunit B.
 
 
 0.924
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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