Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmcALProtein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (383 aa)    
Predicted Functional Partners:
ACZ09556.1
PFAM: major facilitator superfamily MFS_1; KEGG: sbn:Sbal195_1215 sugar (glycoside-pentoside- hexuronide) transporter.
  
    0.813
ACZ09557.1
KEGG: hypothetical protein.
       0.785
ACZ08564.1
KEGG: dal:Dalk_0722 methyltransferase small; Belongs to the methyltransferase superfamily.
 
     0.720
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.708
ACZ09782.1
PFAM: methyltransferase small; KEGG: cju:C8J_0457 hypothetical protein; Belongs to the methyltransferase superfamily.
 
     0.667
ACZ09554.1
PFAM: protein of unknown function DUF214; KEGG: net:Neut_1527 hypothetical protein.
       0.640
ACZ09553.1
PFAM: Peptidase M23; KEGG: cvi:CV_3353 hypothetical protein.
       0.639
ACZ09555.1
PFAM: ABC transporter related; KEGG: cla:Cla_0918 ABC transporter, ATP-binding protein.
       0.623
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.610
ACZ07644.1
Metal dependent phosphohydrolase; KEGG: similar to Dauer Up-Regulated family member (dur-1); TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
  
 0.604
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
Server load: low (26%) [HD]