STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACZ09897.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (153 aa)    
Predicted Functional Partners:
ACZ10949.1
PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: dds:Ddes_1159 HhH-GPD family protein.
 
  
 0.931
ACZ09895.1
PFAM: protein of unknown function UPF0102; KEGG: vvy:VV0603 hypothetical protein; Belongs to the UPF0102 family.
       0.757
ACZ09893.1
KEGG: nse:NSE_0416 putative competence protein F.
     
 0.747
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.741
ACZ09894.1
Hypothetical protein.
       0.731
ACZ09898.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.708
ACZ09202.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
 0.661
ACZ09899.1
Hypothetical protein.
       0.594
ACZ09900.1
KEGG: Viral A-type inclusion protein repeat.
       0.567
ACZ09902.1
Pseudouridylate synthase-like protein; KEGG: abu:Abu_2199 tRNA pseudouridine synthase A.
  
  
 0.546
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.