STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cco:CCC13826_0970 N- (5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (196 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.999
ACZ10143.1
PFAM: Indole-3-glycerol phosphate synthase; KEGG: abu:Abu_0850 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.999
ACZ10141.1
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II.
  
 0.998
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.998
ACZ10140.1
Anthranilate synthase; PFAM: Chorismate binding-like; KEGG: ccv:CCV52592_1683 anthranilate synthase component 1 (anthranilate synthasecomponent I).
 
  
 0.982
ACZ09228.1
Chorismate mutase; KEGG: vsp:VS_0556 P-protein [includes: chorismate mutase,Prephenatedehydratase]; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase.
 
  
 0.634
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family.
     
 0.494
ACZ06988.1
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ade:Adeh_3448 L-threonine ammonia-lyase.
  
  
 0.433
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.428
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.