STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACZ10595.1PFAM: Ham1 family protein; KEGG: bja:bll0673 putative deoxyribonucleotide triphosphate pyrophosphatase. (204 aa)    
Predicted Functional Partners:
ACZ08737.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.841
ACZ06899.1
TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: geo:Geob_2907 phosphodiesterase, MJ0936 family.
 
  
 0.578
nusG
NusG antitermination factor; Participates in transcription elongation, termination and antitermination.
   
    0.545
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
    0.538
folE
GTP cyclohydrolase I; KEGG: cff:CFF8240_1694 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I.
  
  
 0.537
ACZ08739.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.512
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.487
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.470
ACZ10592.1
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: dno:DNO_0610 PTS system, fructose IIC subunit.
       0.456
ACZ10593.1
TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: dat:HRM2_08650 PfkB1; Belongs to the carbohydrate kinase PfkB family.
       0.456
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.