Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACZ10612.1KEGG: dal:Dalk_2955 histidinol phosphate phosphatase HisJ family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.926
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmw:Mmwyl1_1133 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.917
ACZ08711.1
PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
     0.586
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.571
ACZ10268.1
PFAM: PTS system fructose subfamily IIA component; KEGG: kpn:KPN_00552 putative transport protein, PTS system.
  
     0.433
ACZ10266.1
PFAM: phosphotransferase system PTS sorbose- specific IIC subunit; KEGG: spe:Spro_4279 phosphotransferase system PTS sorbose-specific IIC subunit.
  
     0.429
ACZ10267.1
KEGG: spe:Spro_4280 PTS system sorbose subfamily IIB component.
  
     0.423
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: azc:AZC_4502 imidazoleglycerol-phosphate dehydratase.
  
  
 0.415
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.410
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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