STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (107 aa)    
Predicted Functional Partners:
ACZ10968.1
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
  
 0.984
rpmH
TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: smt:Smal_4045 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.972
ACZ10967.1
PFAM: 60 kDa inner membrane insertion protein; KEGG: pca:Pcar_3143 inner-membrane protein.
  
  
 0.971
ACZ10966.1
PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: dal:Dalk_4132 single-stranded nucleic acid binding R3H domain protein.
 
  
 0.915
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  
 0.870
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
     
 0.837
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
    0.817
ACZ10924.1
PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: dal:Dalk_0933 ribosomal protein S1.
 
  
 0.810
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
  
 0.800
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.782
Your Current Organism:
Sebaldella termitidis
NCBI taxonomy Id: 526218
Other names: S. termitidis ATCC 33386, Sebaldella termitidis ATCC 33386, Sebaldella termitidis NCTC 11300, Sebaldella termitidis str. ATCC 33386, Sebaldella termitidis strain ATCC 33386
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.