node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VDBG_00140 | VDBG_00356 | C9S8V6 | C9S5M3 | 3'-5' exonuclease domain-containing protein. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.999 |
VDBG_00140 | VDBG_03648 | C9S8V6 | C9SGP4 | 3'-5' exonuclease domain-containing protein. | RMI1_N domain-containing protein. | 0.991 |
VDBG_00140 | VDBG_04420 | C9S8V6 | C9SJE9 | 3'-5' exonuclease domain-containing protein. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.998 |
VDBG_00140 | VDBG_06033 | C9S8V6 | C9SMA9 | 3'-5' exonuclease domain-containing protein. | Crossover junction endonuclease MUS81. | 0.991 |
VDBG_00140 | VDBG_08292 | C9S8V6 | C9STM1 | 3'-5' exonuclease domain-containing protein. | Replication factor-A protein. | 0.999 |
VDBG_00140 | VDBG_08857 | C9S8V6 | C9SVD2 | 3'-5' exonuclease domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.998 |
VDBG_00140 | VDBG_09315 | C9S8V6 | C9SWP0 | 3'-5' exonuclease domain-containing protein. | Nuclear transport factor 2. | 0.431 |
VDBG_00356 | VDBG_00140 | C9S5M3 | C9S8V6 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 3'-5' exonuclease domain-containing protein. | 0.999 |
VDBG_00356 | VDBG_03648 | C9S5M3 | C9SGP4 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | RMI1_N domain-containing protein. | 0.909 |
VDBG_00356 | VDBG_04420 | C9S5M3 | C9SJE9 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.986 |
VDBG_00356 | VDBG_04764 | C9S5M3 | C9SI82 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | ATP-dependent helicase SGS1. | 0.882 |
VDBG_00356 | VDBG_05582 | C9S5M3 | C9SLA5 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.855 |
VDBG_00356 | VDBG_06033 | C9S5M3 | C9SMA9 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Crossover junction endonuclease MUS81. | 0.855 |
VDBG_00356 | VDBG_07674 | C9S5M3 | C9SRZ9 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | ATP-dependent DNA helicase recQ. | 0.882 |
VDBG_00356 | VDBG_08292 | C9S5M3 | C9STM1 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Replication factor-A protein. | 0.999 |
VDBG_00356 | VDBG_08857 | C9S5M3 | C9SVD2 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.985 |
VDBG_00356 | VDBG_09315 | C9S5M3 | C9SWP0 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Nuclear transport factor 2. | 0.936 |
VDBG_03648 | VDBG_00140 | C9SGP4 | C9S8V6 | RMI1_N domain-containing protein. | 3'-5' exonuclease domain-containing protein. | 0.991 |
VDBG_03648 | VDBG_00356 | C9SGP4 | C9S5M3 | RMI1_N domain-containing protein. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.909 |
VDBG_03648 | VDBG_04420 | C9SGP4 | C9SJE9 | RMI1_N domain-containing protein. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.906 |