STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1447 aa)    
Predicted Functional Partners:
VDBG_05048
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.847
VDBG_02554
Uncharacterized protein.
    
 0.793
VDBG_06212
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.782
VDBG_04790
Proteasome subunit beta.
    
 
 0.777
VDBG_04422
Vacuolar protein sorting-associated protein 26B-B.
    
 
 0.740
VDBG_00101
Proteasome subunit alpha type.
    
 
 0.711
VDBG_02830
Proteasome endopeptidase complex.
    
 
 0.711
VDBG_05144
Proteasome component C5.
    
 
 0.711
VDBG_10007
Proteasome subunit alpha type.
    
 
 0.711
VDBG_00264
AP-1 complex subunit sigma-1.
     
 0.701
Your Current Organism:
Verticillium alfalfae
NCBI taxonomy Id: 526221
Other names: V. alfalfae VaMs.102, Verticillium alfalfae VaMs.102
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