STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa)    
Predicted Functional Partners:
ilvD
KEGG: dde:Dde_0116 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.990
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.982
ACS80058.1
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: dde:Dde_2049 putative alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.978
ACS80358.1
PFAM: aminotransferase class IV; KEGG: dde:Dde_0255 branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase.
  
  
 
0.922
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.918
ACS80496.1
PFAM: homoserine dehydrogenase; Semialdehyde dehydrogenase NAD - binding; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: dde:Dde_2731 homoserine dehydrogenase.
  
 
 0.901
ACS78320.1
PFAM: aminoglycoside phosphotransferase; KEGG: dat:HRM2_21240 phosphotransferase family protein.
   
 
 0.809
ACS80151.1
Pyruvate formate-lyase; KEGG: pca:Pcar_1397 glycerol dehydratase; TIGRFAM: pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
     
  0.800
ACS81574.1
PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; KEGG: dvu:DVU2272 formate acetyltransferase, putative.
     
  0.800
ACS78515.1
PFAM: pyruvate carboxyltransferase; KEGG: dvm:DvMF_2612 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.796
Your Current Organism:
Desulfovibrio salexigens
NCBI taxonomy Id: 526222
Other names: D. salexigens DSM 2638, Desulfovibrio salexigens ATCC 14822, Desulfovibrio salexigens DSM 2638, Desulfovibrio salexigens str. DSM 2638, Desulfovibrio salexigens strain DSM 2638
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