Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Bmur_0076Transcriptional regulator, GntR family; TIGRFAM: trehalose operon repressor; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; KEGG: bhy:BHWA1_00504 trehalose operon repressor; SMART: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH. (235 aa)    
Predicted Functional Partners:
Bmur_0077
PTS system, trehalose-specific IIBC subunit; KEGG: bhy:BHWA1_00503 trehalose PTS system, IIABC component; TIGRFAM: PTS system, trehalose-specific IIBC subunit; PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site; phosphotransferase system EIIC.
 
   
 0.865
Bmur_0253
PTS system, glucose-like IIB subunint; KEGG: bhy:BHWA1_00076 PTS system, IIABC component; TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
 
  
 0.848
Bmur_0078
TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; KEGG: bhy:BHWA1_00502 trehalose-6-phosphate hydrolase; SMART: alpha amylase catalytic sub domain.
 
  
 0.779
Bmur_0791
KEGG: fnu:FN0555 MerR family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.
  
  
 0.678
Bmur_2105
PTS system, glucose subfamily, IIA subunit; KEGG: bhy:BHWA1_02203 fused N-acetyl glucosamine specific PTS enzyme: IIC, IIB, and IIA components; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; sugar- specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site.
 
  
 0.639
Bmur_0498
KEGG: bhy:BHWA1_02631 putative N-acetylglucosamine- 6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; amidohydrolase.
  
  
 0.584
Bmur_0254
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
    0.559
Bmur_0288
PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: bhy:BHWA1_00273 phosphoenolpyruvate-dependent sugar phosphotransferase system.
 
  
 0.556
Bmur_0252
Transcriptional regulator, LacI family; KEGG: bhy:BHWA1_00075 sucrose operon repressor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
  
   
 0.532
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.529
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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