Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
selAL-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (451 aa)    
Predicted Functional Partners:
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
 
  
 0.982
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
     
 0.917
Bmur_0487
KEGG: bhy:BHWA1_00362 selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; Elongation factor SelB winged helix 3; elongation factor Tu domain 2 protein.
 
  
 0.911
Bmur_2431
Selenium metabolism protein YedF; KEGG: bhy:BHWA1_02475 protein of unknown function with an N-terminal SirA-like domain; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA family protein; Belongs to the sulfur carrier protein TusA family.
 
  
 0.728
Bmur_0043
tRNA 2-selenouridine synthase; KEGG: bhy:BHWA1_00445 rhodanese-like domain protein; TIGRFAM: tRNA 2-selenouridine synthase; SMART: Rhodanese domain protein.
 
   
 0.512
Bmur_0601
KEGG: bhy:BHWA1_01026 hypothetical protein.
 
  
 0.452
Bmur_2366
PFAM: Cl- channel voltage-gated family protein; KEGG: bhy:BHWA1_01088 putative chloride channel protein.
  
    0.451
Bmur_0073
KEGG: bhy:BHWA1_00391 hypothetical protein.
   
    0.446
Bmur_2069
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: bhy:BHWA1_02274 potassium uptake protein TrkA.
   
    0.446
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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