Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_0519PFAM: aminotransferase class I and II; KEGG: bhy:BHWA1_00947 aspartate aminotransferase. (398 aa)    
Predicted Functional Partners:
Bmur_0793
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase, type II; KEGG: bhy:BHWA1_02423 prephenate dehydratase; SMART: Chorismate mutase.
 
 
 0.948
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.934
argG
TIGRFAM: argininosuccinate synthase; KEGG: bhy:BHWA1_01491 argininosuccinate lyase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.919
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: bhy:BHWA1_00046 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.916
Bmur_0264
PFAM: aminotransferase class I and II; KEGG: bhy:BHWA1_00840 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
 
  
0.915
Bmur_0423
PFAM: Prephenate dehydrogenase; KEGG: bhy:BHWA1_00719 prephenate dehydrogenase.
  
 
 0.915
Bmur_2782
KEGG: bhy:BHWA1_00140 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SMART: Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.912
Bmur_2709
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bhy:BHWA1_00519 cysteine synthase A.
    
 0.910
Bmur_0820
KEGG: bhy:BHWA1_01224 glutamate synthase (DPH); TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.908
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.908
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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