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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)    
Predicted Functional Partners:
Bmur_2556
KEGG: sfu:Sfum_3948 hypothetical protein.
   
 0.948
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
  
 0.934
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.926
Bmur_2385
TIGRFAM: ribose 5-phosphate isomerase B; sugar- phosphate isomerase, RpiB/LacA/LacB family; KEGG: bhy:BHWA1_01037 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
  
 
 0.924
Bmur_2071
Glucose-1,6-bisphosphate synthase; KEGG: bhy:BHWA1_02285 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III.
  
 0.922
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.921
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
 0.914
Bmur_0244
Transketolase central region; KEGG: bhy:BHWA1_00092 transketolase, pyridine binding subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region.
    
  0.909
Bmur_0245
PFAM: Transketolase domain protein; KEGG: bhy:BHWA1_00091 transketolase N-terminal subunit.
    
 0.908
Bmur_1946
KEGG: bhy:BHWA1_02331 ATP phosphoribosyltransferase regulatory subunit.
  
 
 0.900
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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