STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_0804Na+/Ca+ antiporter, CaCA family; KEGG: bhy:BHWA1_00896 putative Na+/Ca+ exchange protein; TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region. (335 aa)    
Predicted Functional Partners:
Bmur_0803
KEGG: bhy:BHWA1_00897 hypothetical protein.
       0.684
Bmur_0805
PFAM: Thioredoxin domain; KEGG: bhy:BHWA1_02614 thiol-disulfide interchange protein DsbD-like protein.
       0.561
Bmur_0806
PFAM: protein of unknown function DUF255; Thioredoxin domain; KEGG: bhy:BHWA1_02615 thiol-disulfide interchange protein DsbD-like protein.
       0.452
Bmur_2077
PFAM: sodium/hydrogen exchanger; KEGG: bhy:BHWA1_01437 Na(+)/H(+) antiporter.
   
 
 0.452
Bmur_0802
PFAM: Cupin 2 conserved barrel domain protein; KEGG: bhy:BHWA1_00898 cupin domain containing protein.
  
    0.427
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
 
     0.419
Bmur_2358
PFAM: protein of unknown function DUF368; KEGG: bhy:BHWA1_01173 hypothetical protein.
  
     0.414
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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