Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (217 aa)    
Predicted Functional Partners:
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.965
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.958
Bmur_2071
Glucose-1,6-bisphosphate synthase; KEGG: bhy:BHWA1_02285 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III.
 
 
 0.949
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.920
Bmur_2822
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: bhy:BHWA1_00731 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
    
 0.914
Bmur_0245
PFAM: Transketolase domain protein; KEGG: bhy:BHWA1_00091 transketolase N-terminal subunit.
    
 0.902
Bmur_0244
Transketolase central region; KEGG: bhy:BHWA1_00092 transketolase, pyridine binding subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region.
    
  0.901
Bmur_2105
PTS system, glucose subfamily, IIA subunit; KEGG: bhy:BHWA1_02203 fused N-acetyl glucosamine specific PTS enzyme: IIC, IIB, and IIA components; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; sugar- specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site.
    
 0.873
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.871
Bmur_0462
TIGRFAM: pyruvate kinase; KEGG: bhy:BHWA1_00011 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.847
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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