Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (661 aa)    
Predicted Functional Partners:
Bmur_0973
Transcriptional regulator, TraR/DksA family; PFAM: zinc finger DksA/TraR C4-type; KEGG: bhy:BHWA1_02178 DNA-binding transcriptional regulator of transcription, DnaK suppressor protein.
       0.787
Bmur_0392
Formyl transferase domain protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    0.750
Bmur_1341
KEGG: bhy:BHWA1_01602 single-stranded-D-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1.
 
     0.699
Bmur_1321
KEGG: bhy:BHWA1_01032 single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
    
 
 0.659
Bmur_1705
KEGG: bhy:BHWA1_01032 single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
    
 
 0.659
Bmur_1789
KEGG: cts:Ctha_0653 single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
    
 
 0.659
Bmur_2281
KEGG: bhy:BHWA1_01032 single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
    
 
 0.659
Bmur_2378
KEGG: bhy:BHWA1_01032 single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
    
 
 0.659
murB-2
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
     0.643
rpsI
PFAM: ribosomal protein S9; KEGG: bhy:BHWA1_02179 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
       0.639
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.