STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_1069Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (271 aa)    
Predicted Functional Partners:
Bmur_1068
KEGG: bhy:BHWA1_01337 rod shape-determining protein MreB; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl.
 
 
 0.993
Bmur_1070
KEGG: bhy:BHWA1_01339 putative rod shape- determining protein MreD; TIGRFAM: rod shape-determining protein MreD; PFAM: Rod shape-determining protein MreD.
  
 
 0.984
Bmur_2504
TIGRFAM: penicillin-binding protein 2; KEGG: bhy:BHWA1_00775 transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2); PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
 
 
 0.900
Bmur_0735
PFAM: DNA repair protein RadC; KEGG: bhy:BHWA1_00858 putative DNA repair protein RadC.
 
  
 0.833
Bmur_2503
PFAM: cell cycle protein; KEGG: bhy:BHWA1_00776 putative rod shape- determining protein RodA; Belongs to the SEDS family.
 
  
 0.813
Bmur_0017
Peptidoglycan glycosyltransferase; KEGG: bhy:BHWA1_00744 penicillin-binding protein 3; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein.
 
 
 0.800
Bmur_1071
PFAM: adenylate cyclase; KEGG: bhy:BHWA1_01340 CyaB, adenylate cyclase, class 2 (thermophilic).
       0.784
Bmur_0866
KEGG: bhy:BHWA1_01233 hypothetical protein.
 
 
 
 0.700
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
  
 0.609
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.604
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
Server load: low (24%) [HD]