STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)    
Predicted Functional Partners:
Bmur_0462
TIGRFAM: pyruvate kinase; KEGG: bhy:BHWA1_00011 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
 
 0.999
pgk
KEGG: bhy:BHWA1_01680 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 
 0.994
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.983
pgi
KEGG: bhy:BHWA1_01137 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.976
Bmur_2822
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: bhy:BHWA1_00731 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
 0.972
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.967
Bmur_1555
SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: bhy:BHWA1_01681 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.966
Bmur_0856
TIGRFAM: pyruvate, phosphate dikinase; KEGG: bhy:BHWA1_01187 pyruvate phosphate dikinase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; pyruvate phosphate dikinase PEP/pyruvate- binding.
    
 0.927
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.917
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 0.894
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.