Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_1972KEGG: bhy:BHWA1_02187 anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family. (111 aa)    
Predicted Functional Partners:
Bmur_0285
Protein serine phosphatase with GAF(s) sensor(s); KEGG: bhy:BHWA1_00275 serine phosphotase RsbU sigma factor regulatory protein; PFAM: Stage II sporulation E family protein; GAF domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein.
 
 
 0.932
Bmur_2155
Protein serine/threonine phosphatase; KEGG: bhy:BHWA1_02499 serine phosphatase RsbU, regulator of sigma subunit; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.897
Bmur_1938
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
   0.890
Bmur_0966
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: bhy:BHWA1_01544 putative anti-sigma factor.
 
 
 0.872
Bmur_2502
Response regulator receiver modulated serine phosphatase; KEGG: bhy:BHWA1_00777 SpoIIE, stage II sporulation protein E (SpoIIE); PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver.
 
 
 0.853
Bmur_1112
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: bhy:BHWA1_01542 response regulator.
  
 
 0.846
Bmur_0101
KEGG: bhy:BHWA1_00478 hypothetical protein.
  
 
 0.845
Bmur_2596
ABC transporter related protein; KEGG: bhy:BHWA1_00200 ABC-type transport system, ATP-binding component; PFAM: ABC transporter related; SMART: AAA ATPase.
   
 
 0.780
Bmur_0199
KEGG: bhy:BHWA1_00642 anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
  
     0.767
Bmur_0208
PFAM: protein of unknown function DUF140; KEGG: bhy:BHWA1_00630 Ttg2B, ABC-type transport system, permease component; Belongs to the MlaE permease family.
   
 
 0.764
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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