Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_1990KEGG: bhy:BHWA1_02215 hypothetical protein. (1172 aa)    
Predicted Functional Partners:
Bmur_0495
KEGG: bhy:BHWA1_02634 hypothetical protein.
  
     0.774
Bmur_0733
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.774
Bmur_1657
KEGG: bhy:BHWA1_02076 hypothetical protein.
  
     0.774
Bmur_1934
KEGG: bhy:BHWA1_01395 hypothetical protein.
  
     0.774
Bmur_0150
PFAM: Apolipoprotein A1/A4/E; RepA / Rep KID repeat- containing protein; KEGG: bhy:BHWA1_00453 hypothetical protein.
  
     0.773
Bmur_0754
PFAM: Ankyrin; KEGG: bhy:BHWA1_01195 hypothetical protein.
  
     0.773
Bmur_0830
PFAM: TPR repeat-containing protein; KEGG: bhy:BHWA1_01212 hypothetical protein.
  
     0.773
Bmur_2232
KEGG: bhy:BHWA1_02388 TPR domain-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
  
     0.772
Bmur_0638
KEGG: bhy:BHWA1_00940 hypothetical protein.
  
     0.771
Bmur_0075
KEGG: bhy:BHWA1_00505 putative outer membrane component of multidrug efflux.
  
     0.770
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
Server load: low (12%) [HD]