STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_2001KEGG: bhy:BHWA1_02296 D polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. (341 aa)    
Predicted Functional Partners:
Bmur_0036
TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; KEGG: bhy:BHWA1_00584 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein.
  
 0.989
Bmur_0937
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.988
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.983
Bmur_2247
TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: ckr:CKR_P20 hypothetical protein; SMART: Exonuclease.
    
 0.954
Bmur_1989
KEGG: bhy:BHWA1_02213 DNA polymerase III delta prime subunit.
 
 
 
 0.886
Bmur_1778
KEGG: bhy:BHWA1_01527 hypothetical protein; PFAM: TPR repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; Tetratricopeptide repeat.
 
     0.695
Bmur_1970
KEGG: bhy:BHWA1_02185 integral outer membrane protein TolC, efflux pump component.
 
     0.685
Bmur_2000
KEGG: bhy:BHWA1_02295 hypothetical protein.
       0.680
Bmur_0150
PFAM: Apolipoprotein A1/A4/E; RepA / Rep KID repeat- containing protein; KEGG: bhy:BHWA1_00453 hypothetical protein.
 
     0.665
Bmur_0198
KEGG: bhy:BHWA1_00641 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; WD40 domain protein beta Propeller; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
  
     0.661
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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