Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_2008Peptidase M23; KEGG: bhy:BHWA1_02304 putative peptidoglycan- binding LysM:peptidase M23B family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM. (602 aa)    
Predicted Functional Partners:
Bmur_2009
PFAM: acylphosphatase; KEGG: bhy:BHWA1_02305 acylphosphatase.
 
     0.802
Bmur_1938
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
   0.702
Bmur_1087
PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: bhy:BHWA1_01579 putative penicillin binding protein.
 
   
 0.606
Bmur_0782
Signal peptidase I; KEGG: bhy:BHWA1_02481 leader peptidase (signal peptidase I); TIGRFAM: signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
 
  
 0.556
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.532
Bmur_0189
Penicillin-binding protein, 1A family; KEGG: bhy:BHWA1_00340 membrane carboxypeptidase; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase.
 
   
 0.528
Bmur_2010
PFAM: methyltransferase small; KEGG: bhy:BHWA1_02306 methyltransferase small domain protein; Belongs to the methyltransferase superfamily.
       0.517
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.510
Bmur_2518
PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: bhy:BHWA1_00050 penicillin-binding protein 2.
  
     0.508
Bmur_1113
KEGG: bhy:BHWA1_01543 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; NUDIX hydrolase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
  
 0.499
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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