STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_2060PFAM: protein of unknown function DUF583; KEGG: bhy:BHWA1_02265 hypothetical protein. (168 aa)    
Predicted Functional Partners:
Bmur_1938
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
    
 
 0.902
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.722
Bmur_1942
PFAM: Peptidase M23; KEGG: bhy:BHWA1_01423 peptidase.
 
     0.715
Bmur_0107
PFAM: Protein of unknown function DUF2225; KEGG: bhy:BHWA1_00471 hypothetical protein.
  
     0.612
Bmur_1232
Putative transcriptional regulator, Crp/Fnr family; KEGG: bhy:BHWA1_00239 putative cAMP-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.593
Bmur_2737
PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: bhy:BHWA1_00509 L-lactate dehydrogenase.
  
    0.593
Bmur_0176
PFAM: protein of unknown function DUF342; KEGG: bhy:BHWA1_00353 polymerase.
  
     0.555
Bmur_0097
Putative transcriptional regulator, Crp/Fnr family; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat- containing protein; SMART: cyclic nucleotide-binding; Tetratricopeptide repeat.
 
     0.550
Bmur_2521
Flagellar protein FliS; KEGG: bhy:BHWA1_02626 putative flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS.
  
 
 
 0.538
Bmur_2525
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
     0.523
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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