Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_2139PFAM: NUDIX hydrolase; KEGG: bhy:BHWA1_00988 NUDIX hydrolase. (188 aa)    
Predicted Functional Partners:
Bmur_2138
KEGG: bhy:BHWA1_00987 hypothetical protein.
       0.781
Bmur_2140
KEGG: bhy:BHWA1_00989 LepB, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
       0.618
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
       0.471
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.465
Bmur_1635
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; KEGG: bhy:BHWA1_02108 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2.
  
     0.435
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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