Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_2146Peroxiredoxin; Manually curated; manually curated; KEGG: bhy:BHWA1_00995 glutathione peroxidase; Contains selenocysteine; PFAM: glutathione peroxidase; Contains selenocysteine; Belongs to the glutathione peroxidase family. (160 aa)    
Predicted Functional Partners:
Bmur_2487
Gamma-glutamyltransferase; KEGG: bhy:BHWA1_00759 gamma-glutamyltranspeptidase; PFAM: gamma-glutamyltranspeptidase.
    
 0.917
Bmur_0341
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.694
Bmur_0518
Catalase; KEGG: bhy:BHWA1_00919 catalase; PFAM: Catalase related subgroup; Catalase domain protein; Belongs to the catalase family.
  
 
 0.614
Bmur_2147
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.604
Bmur_2047
TIGRFAM: redox-active disulfide protein 2; KEGG: bhy:BHWA1_02249 hypothetical protein.
   
 0.554
Bmur_1555
SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: bhy:BHWA1_01681 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.544
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.515
Bmur_1987
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 
 0.493
Bmur_0379
KEGG: bhy:BHWA1_00426 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
   0.423
Bmur_2731
Peptide-methionine (R)-S-oxide reductase; KEGG: bhy:BHWA1_00581 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.
  
  
 0.420
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.