Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_2149PFAM: protein of unknown function DUF115; KEGG: bhy:BHWA1_00999 hypothetical protein. (577 aa)    
Predicted Functional Partners:
Bmur_2634
PFAM: TPR repeat-containing protein; KEGG: bhy:BHWA1_00796 TPR domain-containing protein.
 
 
 0.888
Bmur_2148
PFAM: pseudouridine synthase; KEGG: bhy:BHWA1_00998 pseudouridine synthase, RsuA/RluD family.
       0.767
Bmur_0733
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
     0.766
Bmur_2768
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; KEGG: bhy:BHWA1_00239 putative cAMP-binding protein.
  
     0.758
Bmur_2633
KEGG: bhy:BHWA1_00795 fibronectin type III domain containing protein; PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein.
  
     0.753
Bmur_2735
PFAM: TPR repeat-containing protein; KEGG: bhy:BHWA1_00511 TPR domain-containing protein.
  
     0.751
Bmur_0094
KEGG: bhy:BHWA1_00486 putative methyl-accepting chemotaxis protein.
  
     0.748
Bmur_2031
KEGG: bhy:BHWA1_02233 radical SAM protein; predicted Fe-S oxidoreductase.
 
     0.747
Bmur_2772
Putative transcriptional regulator, Crp/Fnr family; KEGG: bhy:BHWA1_00244 cAMP-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.747
Bmur_2669
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; KEGG: bhy:BHWA1_02646 cAMP-binding protein.
  
     0.743
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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