Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bmur_2467KEGG: bhy:BHWA1_02472 hypothetical protein; TIGRFAM: cyclically-permuted mutatrotase family protein; PFAM: Kelch repeat-containing protein. (383 aa)    
Predicted Functional Partners:
Bmur_2466
KEGG: bhy:BHWA1_02471 Na+/proline symporter; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
 0.968
Bmur_1914
PFAM: glycosyl hydrolase BNR repeat-containing protein; KEGG: art:Arth_0543 exo-alpha-sialidase.
 
     0.621
Bmur_2712
Hypothetical protein; KEGG: aau:AAur_0636 BNR/Asp-box repeat-containing protein.
 
     0.601
Bmur_0503
Sialidase; KEGG: bhy:BHWA1_00622 sialidase.
 
     0.573
Bmur_2841
PFAM: Protein of unknown function DUF2147; KEGG: bhy:BHWA1_00182 hypothetical protein.
  
     0.478
Bmur_1366
N-acylglucosamine 2-epimerase; KEGG: bhy:BHWA1_01994 N-acyl-D-glucosamine 2- epimerase; PFAM: N-acylglucosamine 2-epimerase.
 
     0.464
Bmur_2468
PFAM: phosphoryl transfer system HPr; KEGG: bhy:BHWA1_00937 phosphocarrier protein HPr.
       0.452
Bmur_2469
PFAM: metallophosphoesterase; KEGG: bhy:BHWA1_00936 putative Metallophos, calcineurin-like phosphoesterase.
       0.434
atpC
ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.413
Bmur_2465
Transcriptional regulator, Crp/Fnr family; KEGG: bhy:BHWA1_02470 putative cAMP-regulatory protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
       0.412
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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