Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Bmur_2575PFAM: serpulina hyodysenteriae variable surface protein; KEGG: bhy:BHWA1_00889 variable surface protein A. (345 aa)    
Predicted Functional Partners:
Bmur_2573
Addiction module toxin, Txe/YoeB family; KEGG: bhy:BHWA1_00152 plasmid encoded toxin Txe; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB.
       0.512
Bmur_2574
Addiction module antitoxin, RelB/DinJ family; KEGG: bhy:BHWA1_00151 DNA-damage-inducible protein J putative; TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin.
       0.512
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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