STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bmur_2693PFAM: aminotransferase class V; KEGG: bhy:BHWA1_00563 serine-pyruvate/aspartate aminotransferase related enzyme. (381 aa)    
Predicted Functional Partners:
Bmur_2694
KEGG: bhy:BHWA1_00562 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; amino acid-binding ACT domain protein; D- isomer specific 2-hydroxyacid dehydrogenase catalytic region.
 
  
 0.751
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.660
purD
TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: bhy:BHWA1_01297 phosphoribosylamine-glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP- grasp (A) domain; Phosphoribosylglycinamide synthetase, N- domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
  
  
 0.648
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
      0.627
Bmur_2569
PFAM: Formiminotransferase-cyclodeaminase; KEGG: bhy:BHWA1_00038 formiminotransferase- cyclodeaminase.
  
  
 0.555
Bmur_2695
TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); KEGG: bhy:BHWA1_00561 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase.
   
 
 0.552
Bmur_2319
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: bhy:BHWA1_02525 FMN-dependent alpha- hydroxyacid oxidizing enzyme.
  
 0.543
Bmur_2692
KEGG: hypothetical protein.
       0.461
Bmur_1641
KEGG: bhy:BHWA1_01628 TPR domain-containing protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
    
  0.431
Bmur_1653
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; KEGG: bhy:BHWA1_01633 TPR domain-containing protein.
    
  0.431
Your Current Organism:
Brachyspira murdochii
NCBI taxonomy Id: 526224
Other names: B. murdochii DSM 12563, Brachyspira murdochii 56-150, Brachyspira murdochii ATCC 51284, Brachyspira murdochii CIP 105832, Brachyspira murdochii DSM 12563, Brachyspira murdochii str. DSM 12563, Brachyspira murdochii strain DSM 12563
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