STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (296 aa)    
Predicted Functional Partners:
Gobs_4564
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro02011 O-succinylbenzoic acid--CoA ligase.
 
  
 0.963
Gobs_0870
PFAM: thioesterase superfamily protein; KEGG: rop:ROP_34540 hypothetical protein.
 
  
 0.935
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
  
 0.912
menA
1,4-dihydroxy-2-naphthoateoctaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.857
Gobs_4561
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: tfu:Tfu_1413 isochorismate synthase.
 
   
 0.836
menC
Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
   
 0.746
Gobs_3202
PFAM: thioesterase superfamily protein; KEGG: sen:SACE_5438 phenylacetic acid degradation- related protein.
 
   
 0.652
Gobs_0332
Hypothetical protein.
       0.551
Gobs_4295
KEGG: mgi:Mflv_4724 mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I.
 
      0.534
Gobs_1739
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rha:RHA1_ro10427 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
   
 0.494
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
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