STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gobs_2253PFAM: response regulator receiver; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SMART: response regulator receiver; KEGG: fal:FRAAL1961 putative thioredoxin reductase. (552 aa)    
Predicted Functional Partners:
Gobs_0116
KEGG: mva:Mvan_1931 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; GAF domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; PAC repeat-containing protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing prot [...]
 
 
 0.998
Gobs_0277
Multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; CHASE3 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; response regulator receiver; histidine kinase HAMP region domain protein; KEGG: mag:amb3735 signal transduction histidine kinase.
  
 
 0.997
Gobs_2254
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; KEGG: nfa:nfa52860 putative two-component system sensor kinase.
 
 
 0.978
Gobs_4814
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: mpo:Mpop_0148 response regulator receiver sensor signal transduction histidine kinase.
 
 
 0.943
Gobs_1520
KEGG: kra:Krad_0334 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.940
Gobs_2068
TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tfu:Tfu_1983 cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.909
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
     
 0.908
Gobs_4046
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: sen:SACE_6136 cystathionine gamma-lyase.
  
 
 0.908
Gobs_5000
KEGG: nca:Noca_3596 hypothetical protein.
   
 
 0.848
Gobs_2251
PFAM: Thioredoxin domain; KEGG: ace:Acel_0542 thioredoxin.
  
 
 0.837
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
Server load: low (12%) [HD]