node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gobs_0523 | Gobs_1356 | Gobs_0523 | Gobs_1356 | PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: saq:Sare_4756 peptidase S1 and S6 chymotrypsin/Hap. | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | 0.461 |
Gobs_0523 | arc | Gobs_0523 | Gobs_2678 | PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: saq:Sare_4756 peptidase S1 and S6 chymotrypsin/Hap. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.836 |
Gobs_0523 | glpK | Gobs_0523 | Gobs_5040 | PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: saq:Sare_4756 peptidase S1 and S6 chymotrypsin/Hap. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.480 |
Gobs_0523 | glpK-2 | Gobs_0523 | Gobs_5042 | PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: saq:Sare_4756 peptidase S1 and S6 chymotrypsin/Hap. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.480 |
Gobs_0658 | Gobs_1356 | Gobs_0658 | Gobs_1356 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: cmi:CMM_1278 putative serine protease. | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | 0.461 |
Gobs_0658 | arc | Gobs_0658 | Gobs_2678 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: cmi:CMM_1278 putative serine protease. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.836 |
Gobs_0658 | glpK | Gobs_0658 | Gobs_5040 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: cmi:CMM_1278 putative serine protease. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.458 |
Gobs_0658 | glpK-2 | Gobs_0658 | Gobs_5042 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: cmi:CMM_1278 putative serine protease. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.458 |
Gobs_1356 | Gobs_0523 | Gobs_1356 | Gobs_0523 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: saq:Sare_4756 peptidase S1 and S6 chymotrypsin/Hap. | 0.461 |
Gobs_1356 | Gobs_0658 | Gobs_1356 | Gobs_0658 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: cmi:CMM_1278 putative serine protease. | 0.461 |
Gobs_1356 | arc | Gobs_1356 | Gobs_2678 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.985 |
Gobs_1356 | glpK | Gobs_1356 | Gobs_5040 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.960 |
Gobs_1356 | glpK-2 | Gobs_1356 | Gobs_5042 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.960 |
Gobs_1356 | prcA | Gobs_1356 | Gobs_2683 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.958 |
Gobs_1356 | prcB | Gobs_1356 | Gobs_2682 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ace:Acel_1689 Mov34/MPN/PAD-1 family protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.958 |
Gobs_2679 | arc | Gobs_2679 | Gobs_2678 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: stp:Strop_2242 hypothetical protein. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.941 |
Gobs_2679 | pafA | Gobs_2679 | Gobs_2684 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: stp:Strop_2242 hypothetical protein. | Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.411 |
Gobs_2679 | prcA | Gobs_2679 | Gobs_2683 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: stp:Strop_2242 hypothetical protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.898 |
Gobs_2679 | prcB | Gobs_2679 | Gobs_2682 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: stp:Strop_2242 hypothetical protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.888 |
Gobs_2679 | pup | Gobs_2679 | Gobs_2680 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: stp:Strop_2242 hypothetical protein. | Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.948 |