| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Gobs_0884 | Gobs_3103 | Gobs_0884 | Gobs_3103 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sco:SCO3182 UTP-glucose-1-phosphate uridylyltransferase. | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | 0.855 |
| Gobs_0884 | Gobs_4701 | Gobs_0884 | Gobs_4701 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sco:SCO3182 UTP-glucose-1-phosphate uridylyltransferase. | KEGG: ace:Acel_0638 UDP-N-acetylglucosamine 2- epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.873 |
| Gobs_0884 | glmU | Gobs_0884 | Gobs_0910 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sco:SCO3182 UTP-glucose-1-phosphate uridylyltransferase. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.915 |
| Gobs_0884 | murA | Gobs_0884 | Gobs_4131 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sco:SCO3182 UTP-glucose-1-phosphate uridylyltransferase. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.843 |
| Gobs_3103 | Gobs_0884 | Gobs_3103 | Gobs_0884 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sco:SCO3182 UTP-glucose-1-phosphate uridylyltransferase. | 0.855 |
| Gobs_3103 | Gobs_4629 | Gobs_3103 | Gobs_4629 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.451 |
| Gobs_3103 | Gobs_4701 | Gobs_3103 | Gobs_4701 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | KEGG: ace:Acel_0638 UDP-N-acetylglucosamine 2- epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.910 |
| Gobs_3103 | glmU | Gobs_3103 | Gobs_0910 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.926 |
| Gobs_3103 | mraY | Gobs_3103 | Gobs_3265 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.439 |
| Gobs_3103 | murA | Gobs_3103 | Gobs_4131 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.900 |
| Gobs_3103 | murB | Gobs_3103 | Gobs_4612 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.954 |
| Gobs_3103 | murC | Gobs_3103 | Gobs_3262 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.566 |
| Gobs_3103 | murF | Gobs_3103 | Gobs_3266 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.465 |
| Gobs_3103 | murG | Gobs_3103 | Gobs_3263 | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.523 |
| Gobs_4629 | Gobs_3103 | Gobs_4629 | Gobs_3103 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Transcriptional regulator, XRE family; PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcv:Bcav_3260 transcriptional regulator, XRE family. | 0.451 |
| Gobs_4629 | glmU | Gobs_4629 | Gobs_0910 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.561 |
| Gobs_4629 | mraY | Gobs_4629 | Gobs_3265 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.929 |
| Gobs_4629 | murA | Gobs_4629 | Gobs_4131 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.850 |
| Gobs_4629 | murB | Gobs_4629 | Gobs_4612 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.752 |
| Gobs_4629 | murC | Gobs_4629 | Gobs_3262 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |