Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Gobs_4282KEGG: fre:Franean1_5842 phosphoribosyltransferase. (259 aa)    
Predicted Functional Partners:
Gobs_0116
KEGG: mva:Mvan_1931 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; GAF domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; PAC repeat-containing protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing prot [...]
  
  
 0.959
xerC
Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
   
    0.833
Gobs_0466
PFAM: Prephenate dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sen:SACE_0231 prephenate dehydrogenase.
   
    0.821
Gobs_3996
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: stp:Strop_1318 DNA protecting protein DprA.
 
 
 0.810
Gobs_1890
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
    0.809
Gobs_0396
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ote:Oter_2770 ABC transporter related.
   
    0.763
Gobs_4322
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cdi:DIP0174 ABC transporter ATP-binding protein.
   
    0.763
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.745
Gobs_3113
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.717
Gobs_4284
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mpa:MAP3359c hypothetical protein.
 
    0.705
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.