Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Gobs_4808KEGG: rop:ROP_16860 hypothetical protein. (339 aa)    
Predicted Functional Partners:
Gobs_0898
KEGG: mpa:MAP2795 hypothetical protein.
  
     0.750
Gobs_3163
KEGG: mav:MAV_4706 hypothetical protein.
  
     0.740
Gobs_3785
PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: fal:FRAAL5813 hypothetical protein.
  
     0.585
Gobs_2220
PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: fal:FRAAL5813 hypothetical protein.
  
     0.574
Gobs_0069
SMART: HNH nuclease; KEGG: fal:FRAAL3457 hypothetical protein.
  
     0.525
Gobs_4933
SMART: HNH nuclease; KEGG: fal:FRAAL3457 hypothetical protein.
  
     0.517
Gobs_3644
PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: fal:FRAAL3381 hypothetical protein.
  
     0.515
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.423
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
       0.423
Gobs_4804
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sen:SACE_7207 heat shock regulator.
       0.400
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
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