Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Gobs_4819PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: mab:MAB_3890c histidine kinase response regulator. (543 aa)    
Predicted Functional Partners:
Gobs_4820
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: ace:Acel_0518 two component LuxR family transcriptional regulator.
 
 0.985
Gobs_0116
KEGG: mva:Mvan_1931 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; GAF domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; PAC repeat-containing protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing prot [...]
  
 
 0.947
Gobs_0277
Multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; CHASE3 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; response regulator receiver; histidine kinase HAMP region domain protein; KEGG: mag:amb3735 signal transduction histidine kinase.
  
 
 0.914
Gobs_4814
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: mpo:Mpop_0148 response regulator receiver sensor signal transduction histidine kinase.
  
 
 0.883
Gobs_1520
KEGG: kra:Krad_0334 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.817
Gobs_0536
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: nca:Noca_2600 uroporphyrinogen-III C- methyltransferase.
       0.757
Gobs_2254
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; KEGG: nfa:nfa52860 putative two-component system sensor kinase.
  
 
 0.726
Gobs_2541
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sma:SAV_4878 two-component system response regulator.
 
 
 0.706
Gobs_2941
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sma:SAV_7392 two-component system response regulator.
 
 
 0.704
Gobs_0155
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; KEGG: tfu:Tfu_0767 LuxR response regulator receiver.
 
 
 0.698
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
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